S.A.G.E. is a collection of programs that perform a wide variety of genetic analyses on both family data and data on unrelated individuals. The range of functionality includes tools for extracting summary statistics describing the data and evaluating general data quality; estimating allele frequencies and testing Hardy-Weinberg proportions; estimating heritability and familial correlations; estimating identity-by-descent (IBD) allele sharing probabilities between relative pairs; performing model-based linkage analysis; performing model-free linkage analysis; performing transmission/disequilibrium (TDT) analysis, and more.
Comments